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1

Neo-functionalism: Obstinate or Obsolete? A Reappraisal in the Light of the New Dynamism of the EC

Tranholm-Mikkelsen, J.

Journal:

Millennium - Journal of International Studies

Year:

1991

Language:

english

File:

PDF, 921 KB

english, 1991

2

Recombinant coagulation factor VIIa labelled with the fac-99 mTc(CO)3-core: synthesis and in vitro evaluation of a putative new radiopharmaceutical for imaging in acute bleeding lesion

Jacob Madsen, Jesper B. Kristensen, Ole H. Olsen, Carsten L. Christoffersen, Lars C. Petersen, Mikael Tranholm, Andreas Kjaer, Birger Hesse

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2011

Language:

english

File:

PDF, 215 KB

english, 2011

3

Determination of creatinine in undiluted blood serum enzymatic flow injection analysis with optosensing

Mette Tranholm Jeppesen, Elo Harald Hansen

Journal:

Analytica Chimica Acta

Year:

1988

Language:

english

File:

PDF, 990 KB

english, 1988

4

Regioselective alkanoylation of cyclodextrins

Donghong Yu, Kim Steffensen, Jesper Tranholm, Anne Louise Nielsen, Reinhard Wimmer, Kim Lambertsen Larsen

Journal:

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Year:

2007

Language:

english

File:

PDF, 323 KB

english, 2007

5

Flow-injection fluorimetric assay of nitrogen-containing substrates by on-line enzymatic generation of ammonia

Mette Tranholm Jeppesen, Elo Harald Hansen

Journal:

Analytica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 1012 KB

english, 1991

6

In vivo models of haemophilia – status on current knowledge of clinical phenotypes and therapeutic interventions

K. ØVLISEN, A. T. KRISTENSEN, M. TRANHOLM

Journal:

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

7

Prevention of haemarthrosis in a murine model of acute joint bleeding

L. A. VALENTINO, N. HAKOBYAN, T. KAZARIAN, B. B. SORENSEN, M. TRANHOLM

Journal:

Year:

2009

Language:

english

File:

PDF, 269 KB

english, 2009

8

IL-1β, IL-6, KC and MCP-1 are elevated in synovial fluid from haemophilic mice with experimentally induced haemarthrosis

K. ØVLISEN, A. T. KRISTENSEN, A. L. JENSEN, M. TRANHOLM

Journal:

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

9

Thrombin generation and platelet activation induced by rFVIIa (NovoSeven®) and NN1731 in a reconstituted cell-based model mimicking haemophilia conditions

M. N. ALJAMALI, M. KJALKE, U. HEDNER, M. EZBAN, M. TRANHOLM

Journal:

Year:

2009

Language:

english

File:

PDF, 285 KB

english, 2009

10

A ferric chloride induced arterial injury model used as haemostatic effect model

F. MØLLER, M. TRANHOLM

Journal:

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

11

Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog

T. KNUDSEN, A. T. KRISTENSEN, T. C. NICHOLS, H. AGERSØ, A. L. JENSEN, M. KJALKE, M. EZBAN, M. TRANHOLM

Journal:

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

12

Pharmacokinetics and pharmacodynamics of a new recombinant FVIII (N8) in haemophilia A mice

T. ELM, D. M. KARPF, K. ØVLISEN, H. PELZER, M. EZBAN, M. KJALKE, M. TRANHOLM

Journal:

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

13

Hemostatic effect of recombinant factor VIIa, NN1731 and recombinant factor VIII on needle-induced joint bleeding in hemophilia A mice

K. ØVLISEN, A. T. KRISTENSEN, L. A. VALENTINO, N. HAKOBYAN, J. INGERSLEV, M. TRANHOLM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

14

Recombinant human factor VIIa and a factor VIIa-analogue reduces heparin and low molecular weight heparin (LMWH)-induced bleeding in rats

B. LAURITZEN, U. HEDNER, P. B. JOHANSEN, M. TRANHOLM, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

15

rFVIIa and a new enhanced rFVIIa-analogue, NN1731, reduce bleeding in clopidogrel-treated and in thrombocytopenic rats

B. LAURITZEN, M. TRANHOLM, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 273 KB

english, 2009

16

Faster onset of effect and greater efficacy of NN1731 compared with rFVIIa, aPCC and FVIII in tail bleeding in hemophilic mice

H. L. HOLMBERG, B. LAURITZEN, M. TRANHOLM, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

17

GlycoPEGylated rFVIIa (N7-GP) has a prolonged hemostatic effect in hemophilic mice compared with rFVIIa

H. HOLMBERG, T. ELM, D. KARPF, M. TRANHOLM, S. E. BJØRN, H. STENNICKE, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 144 KB

english, 2011

18

Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogs

Bo Wiinberg, Asger L. Jensen, Elizabeth Rozanski, Pär I. Johansson, Mads Kjelgaard-Hansen, Mikael Tranholm, Annemarie T. Kristensen

Journal:

The Veterinary Journal

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

19

Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity

Bo Wiinberg, Asger L. Jensen, Pär I. Johansson, Mads Kjelgaard-Hansen, Elizabeth Rozanski, Mikael Tranholm, Annemarie T. Kristensen

Journal:

The Veterinary Journal

Year:

2010

Language:

english

File:

PDF, 262 KB

english, 2010

20

Canine specific ELISA for coagulation factor VII

Tom Knudsen, Mads Kjelgaard-Hansen, Mikael Tranholm, Bo Wiinberg, Jes T. Clausen, Jens Jacob Hansen, Timothy C. Nichols, Marianne Kjalke, Asger L. Jensen, Annemarie T. Kristensen

Journal:

The Veterinary Journal

Year:

2011

Language:

english

File:

PDF, 543 KB

english, 2011

21

A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

A. E. PASTOFT, J. LYKKESFELDT, M. EZBAN, M. TRANHOLM, H. C. WHINNA, B. LAURITZEN

Journal:

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

22

Pharmacokinetics and pharmacodynamics of rFVIIa and new improved bypassing agents for the treatment of haemophilia

HENRIK AGERSØ, MIKAEL TRANHOLM

Journal:

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

23

Implementation of the ISTH classification of non-overt DIC in a thromboplastin induced rabbit model

Line Olrik Berthelsen, Annemarie Thuri Kristensen, Bo Wiinberg, Mikael Tranholm

Journal:

Thrombosis Research

Year:

2009

Language:

english

File:

PDF, 657 KB

english, 2009

24

Purified thromboplastin causes haemostatic abnormalities but not overt DIC in an experimental rabbit model

Line Olrik Berthelsen, Annemarie T. Kristensen, Mikael Tranholm

Journal:

Thrombosis Research

Year:

2010

Language:

english

File:

PDF, 900 KB

english, 2010

25

Animal models of DIC and their relevance to human DIC: A systematic review

Line Olrik Berthelsen, Annemarie T. Kristensen, Mikael Tranholm

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 536 KB

english, 2011

26

Prolonged half-life of glycoPEGylated rFVIIa variants compared to native rFVIIa

Ditte M. Karpf, Brit B. Sørensen, Mette B. Hermit, Heidi L. Holmberg, Mikael Tranholm, Britta V. Bysted, Andreas V. Groth, Søren E. Bjørn, Henning R. Stennicke

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 409 KB

english, 2011

27

Recombinant factor VIIa reduces bleeding in severely thrombocytopenic rabbits

Mikael Tranholm, Rasmus Rojkjaer, Charles Pyke, Annemarie T. Kristensen, Birgitte Klitgaard, Karsten Lollike, Morris A. Blajchman

Journal:

Thrombosis Research

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

28

Thromboelastographic Evaluation of Hemostatic Function in Dogs with Disseminated Intravascular Coagulation

Wiinberg, B., Jensen, A.L., Johansson, P.I., Rozanski, E., Tranholm, M., Kristensen, A.T.

Journal:

Journal of Veterinary Internal Medicine

Year:

2008

Language:

english

File:

PDF, 180 KB

english, 2008

29

Automated registration of tail bleeding in rats

Johansen, Peter B., Henriksen, Lars, Andresen, Per R., Lauritzen, Brian, Jensen, Kåre L., Juhl, Trine N., Tranholm, Mikael

Journal:

Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 369 KB

english, 2008

30

Haemostatic alterations in a group of canine cancer patients are associated with cancer type and disease progression

Eva B Andreasen, Mikael Tranholm, Bo Wiinberg, Bo Markussen, Annemarie T Kristensen

Journal:

Acta Veterinaria Scandinavica

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

31

Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, J., Lauritzen, B.

Journal:

Year:

2013

Language:

english

File:

PDF, 271 KB

english, 2013

32

A novel F8 −/− rat as a translational model of human hemophilia A

Nielsen, L. N., Wiinberg, B., Häger, M., Holmberg, H. L., Hansen, J. J., Roepstorff, K., Tranholm, M.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 3.27 MB

english, 2014

33

Expression of tissue factor in canine mammary tumours and correlation with grade, stage and markers of haemostasis and inflammation

Andreasen, E. B., Nielsen, O. L., Tranholm, M., Knudsen, T., Kristensen, A. T.

Journal:

Veterinary and Comparative Oncology

Year:

2014

Language:

english

File:

PDF, 909 KB

english, 2014

34

Buprenorphine does not impact the inflammatory response in haemophilia A mice with experimentally-induced haemarthrosis

Groth, M., Kristensen, A., Ovlisen, K., Tranholm, M.

Journal:

Laboratory Animals

Year:

2014

Language:

english

File:

PDF, 351 KB

english, 2014

35

Impact of blood sampling technique on blood quality and animal welfare in haemophilic mice

Holmberg, H., Kiersgaard, M. K., Mikkelsen, L. F., Tranholm, M.

Journal:

Laboratory Animals

Year:

2011

Language:

english

File:

PDF, 395 KB

english, 2011

36

Novel, high incidence exercise-induced muscle bleeding model in hemophilia B mice: rationale, development and prophylactic intervention

Tranholm, M., Kristensen, A. T., Broberg, M. L., Groth, M. P.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 642 KB

english, 2015

37

Development of a flow cytometric assay for detection of coated platelets in dogs and evaluation of binding of coated platelets to recombinant human coagulation factor VIIa

Knudsen, Tom, Kjalke, Marianne, Tranholm, Mikael, Nichols, Timothy C., Jensen, Asger L., Kristensen, Annemarie T.

Journal:

American Journal of Veterinary Research

Year:

2011

File:

PDF, 592 KB

2011

38

Development of a flow cytometric assay for detection of coated platelets in dogs and evaluation of binding of coated platelets to recombinant human coagulation factor VIIa

Knudsen, Tom, Kjalke, Marianne, Tranholm, Mikael, Nichols, Timothy C., Jensen, Asger L., Kristensen, Annemarie T.

Journal:

American Journal of Veterinary Research

Year:

2011

Language:

english

File:

PDF, 592 KB

english, 2011

39

Development of a tail vein transection bleeding model in fully anaesthetized haemophilia A mice - characterization of two novel FVIII molecules

Johansen, P. B., Tranholm, M., Haaning, J., Knudsen, T.

Journal:

Year:

2016

Language:

english

File:

PDF, 403 KB

english, 2016

40

Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

Lövgren, K. M., Søndergaard, H., Skov, S., Weldingh, K. N., Tranholm, M., Wiinberg, B.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2016

Language:

english

File:

PDF, 486 KB

english, 2016

41

The F8 −/− rat as a model of hemophilic arthropathy

Sørensen, K. R., Roepstorff, K., Wiinberg, B., Hansen, A. K., Tranholm, M., Nielsen, L. N., Kjelgaard-Hansen, M.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2016

Language:

english

File:

PDF, 804 KB

english, 2016

42

rFVIIa and NN1731 Reduce Bleeding in Hydroxyethyl Starch Hemodiluted Rabbits

Lauritzen, Brian, Viuff, Dorthe, Tranholm, Mikael, Ezban, Mirella

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

2010

Language:

english

File:

PDF, 2.08 MB

english, 2010

43

Prolonged effect of GlycoPEGylated rFVIIa (40k-PEG-rFVIIa) in rabbits correlates to activity in plasma

Johansen, Peter B., Bjørn, Søren E., Agersø, Henrik, Thorup, Inger, Hermit, Mette B., Sørensen, Brit B., Stennicke, Henning R., Ezban, Mirella, Tranholm, Mikael

Journal:

Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 117 KB

english, 2010

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